Joshua P. Gray, Ph.D.

Education & Training
Professor and Section Chief of Chemistry, Department of Science, United States Coast Guard Academy

Full biography

Recent Publications

Gray, JP, Bildik, G, Kim, HN, Sutton, MN, Wang, J, Osuji, AO et al.. DIRAS3-derived cyclic peptides disrupt KRAS-RAF interaction and KRAS nanoclustering, suppressing KRAS-driven pancreatic and ovarian tumors. iScience. 2025;28 (11):113686. doi: 10.1016/j.isci.2025.113686. PubMed PMID:41244592 PubMed Central PMC12616096.

Aleksunes, LM, Gray, JP, Meshanni, J, Laskin, JD, Laskin, DL. Repurposing FDA-approved drugs to treat chemical weapon toxicities: Interactive case studies for trainees. Pharmacol Res Perspect. 2024;12 (4):e1229. doi: 10.1002/prp2.1229. PubMed PMID:38965070 PubMed Central PMC11223991.

Hall, GJ, Page, EJ, Rhee, M, Hay, C, Krause, A, Langenbacher, E et al.. Wastewater Surveillance of US Coast Guard Installations and Seagoing Military Vessels to Mitigate the Risk of COVID-19 Outbreaks, March 2021-August 2022. Public Health Rep. 2024;139 (6):699-707. doi: 10.1177/00333549241236644. PubMed PMID:38561999 PubMed Central PMC11504356.

Bildik, G, Gray, JP, Mao, W, Yang, H, Ozyurt, R, Orellana, VR et al.. DIRAS3 induces autophagy and enhances sensitivity to anti-autophagic therapy in KRAS-driven pancreatic and ovarian carcinomas. Autophagy. 2024;20 (3):675-691. doi: 10.1080/15548627.2023.2299516. PubMed PMID:38169324 PubMed Central PMC10936598.

Liang, X, Jung, SY, Fong, LW, Bildik, G, Gray, JP, Mao, W et al.. Membrane anchoring of the DIRAS3 N-terminal extension permits tumor suppressor function. iScience. 2023;26 (11):108151. doi: 10.1016/j.isci.2023.108151. PubMed PMID:37915607 PubMed Central PMC10616557.

Gray, JP, Uddin, MN, Chaudhari, R, Sutton, MN, Yang, H, Rask, P et al.. Directed evolution of cyclic peptides for inhibition of autophagy. Chem Sci. 2021;12 (10):3526-3543. doi: 10.1039/d0sc03603j. PubMed PMID:34163626 PubMed Central PMC8179393.

Casillas, RP, Tewari-Singh, N, Gray, JP. Special issue: emerging chemical terrorism threats. Toxicol Mech Methods. 2021;31 (4):239-241. doi: 10.1080/15376516.2021.1904472. PubMed PMID:33730980 PubMed Central PMC10728888.

Klionsky, DJ, Abdel-Aziz, AK, Abdelfatah, S, Abdellatif, M, Abdoli, A, Abel, S et al.. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)¹. Autophagy. 2021;17 (1):1-382. doi: 10.1080/15548627.2020.1797280. PubMed PMID:33634751 PubMed Central PMC7996087.

Neumeister, SM, Gray, JP. The Strategic National Stockpile: identification, support, and acquisition of medical countermeasures for CBRN incidents. Toxicol Mech Methods. 2021;31 (4):308-321. doi: 10.1080/15376516.2020.1853294. PubMed PMID:33208007 PubMed Central PMC10754051.

Engel, BJ, Grindel, BJ, Gray, JP, Millward, SW. Purification of poly-dA oligonucleotides and mRNA-protein fusions with dT₂₅-OAS resin. Bioorg Med Chem Lett. 2020;30 (4):126934. doi: 10.1016/j.bmcl.2019.126934. PubMed PMID:31919017 PubMed Central PMC6986445.